Answer in Organic Chemistry for Mahjabin #221745
Alanine can be synthesized from pyruvate and branched chain amino acids such as valine, leucine, and isoleucine. Alanine is produced by reductive amination of pyruvate, a two-step process. In the first step, α-ketoglutarate, ammonia and NADH are converted by glutamate dehydrogenase to glutamate, NAD+ and water.
The preparation of alanine from propionic acid, first by bromination via the Hell–Volhard–Zelinsky halogenation to form 2-bromopropanoic acid and then ammonolysis to the racemate of the amino acid.